Saturday, December 26, 2009

Redheads, Inflammation, and Celiac Disease

As I mentioned in previous blogs, when the gene for the melanocortin 1 receptor (MC1R) does not work on skin melanocyte cells, it causes the individual to have red hair and fair skin. But recent studies show that MC1R is not only expressed on skin melanocyte cells, where it determines pigment. It is also expressed on antigen-presenting and other immune cells, including monocytes, macrophages, mast cells, T and B cells and dendritic cells, where its primary role is to down regulate inflammation and allergic response. Basically, when these cells encounter an inflammatory environment, they increase the number of MC1 receptors and produce more α-melanocyte stimulating hormone (α-MSH) to put out the fire. Since the MC1 receptor genetically doesn’t function in the skin melanocyte cells of redheads, then can it conceivably be hypothesized that it also doesn’t function, or that its function is significantly compromised, in these other immune cells where it also appears, possibly compromising a redhead's defense against allergic and inflammatory conditions? One possible example of an allergic and inflammatory condition to which redheads might be vulnerable is Celiac Disease.

Redheads and Celiac Disease

When I first started researching redheads and health, one of the first studies I encountered related Celiac Disease to the melanocortin 1 receptor, the gene responsible for red hair. At the time, my sister who is a redhead had recently been diagnosed with Celiac Disease, and I wondered if there was some sort of connection between the two. Celiac Disease is a food intolerance to a gluten protein found in grains including wheat, rye, oats, barley, triticale, spelt, and kamut. It affects approximately 1 in 133 Americans, and it causes damage to the intestinal villi, which results in malabsorption of nutrients and intestinal permeability (leaky gut), which may lead to other food allergies or intolerances. Celiac Disease is considered to be a multi-system, multi-symptom disorder. Celiac Disease is strongly associated with the human leukocyte antigen (HLA) molecule, which is a gene encoded on alleles DQ2 and DQ8. Approximately 92 to 98 percent of patients with Celiac Disease carry the HLA-DQ2 gene, while the remaining 2 to 8 percent of cases carry the HLA-DQ8 gene. Celiac Disease symptoms are extremely varied, can often mimic other bowel disorders and are not always gastrointestinal. Infants, toddlers, and young children often exhibit growth failure, vomiting, bloated abdomen and behavioral changes. Symptoms of Celiac Disease may include one or more of the following:

* Abdominal cramps, gas and bloating
* Anemia
* Borborygmi (stomach rumbling)
* Coetaneous bleeding
* Diarrhea
* Easy bruising
* Epitasis (nose bleeding)
* Failure to thrive
* Fatigue or general weakness
* Flatulence
* Fluid retention
* Foul-smelling or grayish stools that are often fatty or oily
* Gastrointestinal symptoms
* Gastrointestinal hemorrhage
* Hematuria (red urine)
* Hypocalcaemia/ hypomagnesaemia
* Infertility
* Iron deficiency anemia
* lymphocytic gastritis
* Muscle weakness
* Muscle wasting
* Nausea
* No obvious physical symptoms (just fatigue, overall not feeling well)
* Osteoporosis
* Pallor (unhealthy pale appearance)
* Panic Attacks
* Peripheral neuropathy (nerve damage)
* Stunted growth in children
* Vertigo
* Vitamin B12 deficiency
* Vitamin D deficiency
* Vitamin K deficiency
* Vomiting
* Voracious appetite
* Weight loss
* Obesity

In a study by Colombo et al. regarding Celiac Disease, it was found that the production of α-MSH and the activity of MC1 receptors in the goblet cells of the damaged atrophic intestinal villi of untreated Celiac patients significantly increased when exposed to gliadin (a glycoprotein of gluten). It was postulated that this increased activity was for the purpose of putting out the fire of inflammation and protecting the gut from further damage. The study suggested that if a Celiac patient has poor compliance with a gluten-restrictive diet, the administration of pharmaceutical α-MSH might be therapeutic. But were there any redheads with Celiac Disease in the study? If so, did they also exhibit enhanced production of α-MSH and MC1 receptor activity? In general, do the MC1 receptors on goblet cells in the intestine of a redhead also work to protect them from the damage of inflammation since this receptor is known not to work on the skin melanocyte cells of redheads?

It should be noted that both the Celiac Disease genes and the red hair gene are common to those of European ancestry. Those who are born with and continue to have flaming red hair through adulthood are “hard-wired” genetically to have loss of function of MC1R in skin melanocyte cells and possibly immune cells; whereas, the Celiac Disease genes may be asymptomatic, latent or silent and then turn on like a “lightswitch” due to adverse environmental or lifestyle conditions. Redheads with genetic Celiac Disease markers may not have the defense of fully functioning MC1 receptors on immune cells in the digestive tract to protect them and may be predisposed to gastrointestinal inflammation, which creates a stressful environment that could ultimately cause the Celiac Disease genes to come out of latency. In other words, just as the exterior skin of a redhead is vulnerable to damage from ultraviolet radiation from the sun, the interior “skin” or intestinal tract of a redhead might also be vulnerable to the stress and damage of everyday digestion. It’s possible that if redheads with Celiac Disease gene markers are not following a gluten-restrictive diet, not only would the fire of inflammation in the intestinal tract rage on, but also the proposed treatment with the pharmaceutical α-MSH hormone might be ineffectual.

I suggest that if you are a redhead, and most especially if you are exhibiting any symptoms of Celiac Disease noted above, that you get tested. There are a few tests that you can take:

*A genetic DNA test - this will tell you whether you have a genetic tendency towards the disease

*A blood test for Celiac Disease immune markers - this test indicates whether you might be having an immune reaction to gluten.

*A biopsy of the small intestine - this is the only test that can confirm whether you indeed have developed Celiac Disease. You must be eating gluten regularly at the time of the test for it to be accurate. Full atrophy and partial atrophy of the intestinal villi confirms that you are reacting to gluten. (Please note that some doctors only recognize full atrophy of the intestinal villi as confirmation of Celiac Disease so be sure to get a copy of the test results.)

If a redhead has a genetic predisposition towards Celiac Disease, a lifelong gluten-restrictive diet (avoiding wheat, rye, oats, barley, triticale, spelt, kamut) may be a preventive measure to ensure long-term health and vitality. Long-term consequences of undiagnosed Celiac Disease can lead to intestinal cancer, neurological and autoimmune disorders, and even death. For support and more information, please visit www.celiac.com and www.celiac.org. Please also see Therapeutic Diets for Redheads.

Even if a redhead does not have the Celiac Disease gene markers, wheat and glutinous grains can still cause allergies or gastro-intestinal disturbances due to their difficulty to digest and their over-consumption in the modern diet, particularly of wheat. If a redhead does not have the Celiac Disease genes, but is still showing signs of allergy or intolerance to gluten or wheat, one or both may need to be removed from the diet for three to six months, introduced and observed for reaction (provocatively tested), and if no reaction, included on rotation every fourth day. Whole grains that are soaked overnight with lemon juice or whey or fermented then cooked may be better tolerated than those that are not. Many redheads may also happily partake of non-glutinous organic grains such as brown or wild rice, quinoa, millet, buckwheat, teff or amaranth. Minimal consumption of grains is recommended for redheads depending on their sensitivities.

Glutinous grains, especially refined glutinous grains, are usually over-consumed and one of the biggest culprits for weight gain, so restricting gluten may have the added benefit of weight loss. But in case you need that chocolate chip cookie or cake for an occasional indulgence, there a lot of delicious gluten-free options available now. Look for boxes that are marked "gluten-free" in your local natural grocery. There are also some great specialty bakeries in more urban areas available.

I myself have never gotten a DNA test to see if I have the gene for Celiac Disease. After my sister was diagnosed, I did get a blood test which showed that I had high anti-gliadin antibodies which indicated some sort of allergic reaction to gluten. Since other autoimmune diseases run in my family, including Multiple Sclerosis, and since my sister has a confirmed case of Celiac Disease, I decided to restrict gluten from my diet, and I'm so happy that I did! I feel that a gluten-restrictive diet was very instrumental to my resolving my digestive problems. Somehow I still found a way to occasionally indulge in cookies, cake, and pizza -- as the 20 pounds I've recently gained keep reminding me, but for me that's a good thing, because my Celiac Disease symptom was weight loss. I was too thin! So it all worked out.

Some supportive books, blogs, and websites for Celiac Disease and digestion:

www.celiac.com

www.celiac.org

Gluten Free Girl and the Chef Blog

Dr. Doherty's C-liac Vitality Supplement Packets

23 comments:

  1. Hi,
    My daughter is 9 and has red hair. She had and endoscopy and colonoscopy last year which "ruled out" celiac disease. Her antigliadin antibody was 80 intitially and after going gluten free, has RISEN to over 100. My daughter has dental enamel defects as well. She has upcoming dental work to fill 3 cavities and try to salvage her 6 year molar. She had poor pain control when the filling was placed initially. I have read that redheads need more anesthetic for procedures (the GI doc agreed, but our dentist seems to think she can't possibly be having pain during the procedures as she has been given so much novacaine.
    Any thought?
    Thanks, Lisa

    ReplyDelete
    Replies
    1. I am a 51 year old female that just found out I have Parkinson's about a year and half, but I have been having signs of it for years, tremors, depression, body weakness. ECT. I honestly don't think my doctor was reading the signs because of my gender and age. A few years ago I had my shoulder lock up on me and I was sent to a P.T since x-rays didn't show any physical damage. My shaking was getting worse and I began falling. Only when my speech became so bad that it brought concern to my dentist was Parkinson's even considered. He phoned my doctor with his concerns about my shaking and balance problems. By this time I was forgoing shots in the back of my neck for back and neck pain to which once again I was sent to a P.T (although x-rays showed no damage) I was told I had a few spurs which were most likely causing the pain. Here I was feeling like my whole body was falling apart and doctor could not find anything wrong, maybe in was all in my head? My doctor even seemed annoyed with me and things just kept progressing and I just kept it to myself, why bother going through testing and them finding nothing? Well, it was after my second P.T called my doctor about the weakness in my legs and arms, by this time I have developed a gait in my walk and I fell more frequently. Only then did my doctor send me to a specialist and it was found that I had Parkinson's, and that I have had it for awhile. I think because I was a woman that my signs and symptoms weren't taken seriously and therefor left untreated for so long,I was taking pramipexole dihydrochloride three times daily, I Was on carbidopa levodopa but only lasted 90 minutes then wore off.I found that none of the current medications worked effective for me.I got tired of using those medication so I decided to apply natural herbs formula that was prescribed to me by my second P.T, i purchase the herbal formula from totalcureherbsfoundation. com, There has been huge progression ever since I start the treatment plan which will last for 15 weeks usage.all the symptoms and sign has begin to disappear .

      Delete
    2. I’m recommending Dr Godday to everyone who have herpes virus to get the cure from him. I was diagnose of genital herpes in 2015 and i have been searching and asking questions to see if i could get something to cure the disease because i did not believe what the doctors say that no cure is found yet. I came across a comment on Youtube and the person testify how she was cured from herpes and hpv after using Dr Godday herbal medicine. I quickly contact Dr email and explain my problem to him and he prepare the herbs and send it to me through courier and gave me instructions on how to use it and tell me to go for checkup after usage which i did after two weeks of taken the herbal medicine and my result was NEGATIVE. I waited another month and retested the result was still NEGATIVE and my doctor told me that am completely free from herpes. Am so happy and grateful to Dr Godday for what he has done for me and i will continue to share this for people out there to know that there is cure for herpes. You can contact Dr Godday on email and WhatsApp to get the cure from him. Email:goddayspiritualhome@gmail.com Or Call/What’s-app +1{919}4956404

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  2. Hi Lisa,
    I apologize for taking so long to get back to you. My father recently passed away and I was out of town.

    May I ask what were the original symptoms that caused your doctor to order an endoscopy and colonoscopy? I recommend getting a copy of the endoscopy and colonoscopy lab results and examining them more closely. I heard a speaker at the NANP conference mention that some physicians only consider it to be Celiac Disease if there is full atrophy of the intestinal villi (as opposed to partial atrophy), yet partial atrophy can also cause symptoms. A second opinion could always be helpful or you may consider consulting a complimentary holistic practitioner such as a naturopath who can do additional preventive testing such as a comprehensive diagnostic stool analysis test. This is a test that western medical doctors normally do not do.

    Sometimes it is helpful to also go casein/dairy free initially until the inflammation calms down (in addition to going gluten free). A colleague of mine named Julie Matthews at Healthful Living does nutrition consulting for children and often recommends a gluten/casein free diet. http://www.healthfulliving.org/holistic/children/.

    I've never heard of antigliadin readings rising after going gluten free, but there are so many ingredients with gluten that you have to be very diligent in reading all labels to avoid it. At www.celiac.com, there is an unsafe and safe food list posted. With a 9 year old it may be very difficult to follow a strict gluten-free and/or dairy free diet. There may be cross contamination with glutinous foods within your kitchen e.g. using the same butter, toaster, silverware, etc. You will need to keep her food and possibly her utensils, plates completely separate. She may also be getting gluten accidentally at school or over at friends’ houses because she likely misses it and craves it. You may also consider reducing refined sugars and simple carbohydrates as they also can contribute to gut inflammation. I realize that a 9 year old can be a very picky eater so do your best.

    Regarding dentistry, you may consider consulting a holistic dentist who does not use amalgam fillings. Amalgams have a small amount of mercury in them, and it has been debated whether amalgam fillings are healthy to use in the same way that it is debated whether thimerosal in vaccines is safe to use. I don’t really know if it is true or not. I haven’t researched it (Julie has) but why take the risk?

    Regarding pain, please also read my blog post Redheads and Pain Tolerance:
    http://blessedwithred.blogspot.com/2009/08/redheads-and-pain-tolerance.html

    Good luck and I hope that this information is helpful.
    Carolbetty

    ReplyDelete
  3. Some helpful books:
    http://www.amazon.com/dp/0969276818?tag=blesstheresgu-20&camp=213761&creative=393545&linkCode=bpl&creativeASIN=0969276818&adid=0Y63A3TE3Y4YJRRM2VPM&

    http://www.amazon.com/Digestive-Wellness-Strengthen-Digestion-Completely/dp/0071441964/ref=sr_1_1?s=gateway&ie=UTF8&qid=1285742713&sr=8-1

    ReplyDelete
  4. Hi,
    I have two sons with red hair, the oldest is 4 1/2 and has your color exactly! He was diagnosed with hydrocephalus at 4 months, type 1 diabetes at 12 months (at which time the doctors said his hydrocephalus had resolved on it's own), peanut and egg allergies at 14 months, mild asthma when he has a respiratory virus at 3 years old and dust and cat allergies at four years old. He also suffers from excema, it comes and goes. He has been tested for celiac and thyroid disorders, not because he was showing any real symptoms but because they are often standard tests for diabetics. I was just wondering if you have come across any research that shows a link between red hair and type 1 diabetes? All of his stuff is autoimmune and I have always wondered if the red hair plays a part in any of it. I also have a two year old son who so far only has mild excema and intermittent asthma when he gets a cold. If it is relevant at all Miles who has diabetes has blue/grey eyes and Felix the youngest has brown eyes. I have brown hair and my husband has dark brown hair with a bit of red in his beard. He was also diagnosed with type 1 last spring and has mild asthma.
    Thanks!
    Liz

    ReplyDelete
  5. I just read my comment and should have clarified that his thyroid and celiac tests came back negative. They will test him every year.
    Liz

    ReplyDelete
  6. Dear Liz,
    I apologize that it has taken me so long to respond to you. You have 2 redheaded sons! My! You are blessed indeed! They must be very precious to you and quite a colorful handful.

    I have not done research on correlation between redheads and type 1 diabetes. It sounds like type 1 diabetes may be genetic on your husband’s side of the family, is that correct? Both the red hair gene and type 1 diabetes (a combination of genes) are common to those of European ancestry. As I mention above, red hair may create an inflammatory environment and when adding another autoimmune genetic component like type 1 diabetes to the mix then problems may be more likely to surface and those genes switch on.

    What kind of Celiac tests are they giving your son - is it a DNA test? a blood test? or a small intestine biopsy? Only a biopsy can confirm Celiac Disease and some doctors think that full destruction of the intestinal villi is Celiac Disease, and that partial destruction of the villi is not Celiac Disease. However, partial destruction of villi may indicate a gluten sensitivity and a gluten free diet may be helpful. It is important to read and research the lab test results and what the readings mean. Also, it is important to note that wheat and gluten can also cause other types of reactions besides intestinal - skin, behavioral etc. My skin has been much better since being off of gluten.

    You can always try a casein/gluten free diet as an experiment and see if it helps calm anything down (I include books in my blog). What might also be helpful is Vitamin D-3 supplementation (600 IU daily) unless they are getting a lot of daily sun but probably not because their skin would burn to a crisp! Poor babies!

    Also try some pro-biotic supplements like Jarrow Formulas Yum Yum dolpholus. The max recommended on the box is 4 a day. http://www.jarrow.com/product/279/Yum_Yum_Dophilus

    ReplyDelete
  7. Wow! I'm so glad to find this post. I'm a redhead and struggling with some issues I am pretty sure are related to wheat. Have pretty intense muscle pain/tightness that just seemed like a chronic thing and part of the aging process (I'm only 36). Experimented to try to see if anything changed it and went of wheat. Had it accidentally after being off it for 2 weeks and had a reaction within an hour (!). Going to see a rhumatologist after 2 positive ANA blood tests (negative celiac blood test). Will follow some of the leads you suggested. Thanks!

    ReplyDelete
  8. I am a redheaded female; at 65 mostly red and white. I am of Swedish and Northern German descent. Red hair runs on both sides of my family with 3 of my grandparent's having had red hair. There are many autoimmune diseases that run in our family. I had Guillain Barre Syndrome 11 years ago. Was wondering if you have any knowledge of the relationship to redhair and the disorder? I was reminded of this yesterday on Andy Griffiths' passing. I remember that he also had GBS in his life, and have noticed as a younger man he had a dark reddish head of hair

    ReplyDelete
  9. Hello, thank you for this post. I belong to a group of Apraxia/ Autism parents on facebook and we are making the common observation that many children with apraxia tend to have red hair, or have a parent with red hair. I am going to post this article today. Thanks again.

    ReplyDelete
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    ReplyDelete
  11. I was diagnosed with Parkinson’s disease a year ago at the age of 55. For several months I had noticed tremors in my right hand and the shaking of my right foot when I was sitting. My normally beautiful cursive writing was now small cramped printing. And I tended to lose my balance. Neurologist had me walk down the hall and said I didn’t swing my right arm. I had never noticed! I was in denial for a while as there is no history in my family of parents and five siblings, but now accept I had classic symptoms. I was taking pramipexole (Sifrol), carbidopa/levodopa and Biperiden, 2 mg. and started physical therapy to strengthen muscles. nothing was really working to help my condition. I went off the Sifrol (with the doctor’s knowledge) and started on Parkinson's herbal formula i ordered from www.solutionhealthherbalclinic.com, my symptoms totally declined over a 7 weeks use of the Parkinson's disease natural herbal formula. I am now almost 60 and doing very well, the disease is totally reversed!! Visit there website www.solutionhealthherbalclinic.com OR E-mail: info@solutionhealthherbalclinic.com

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  12. My symptoms started at the age of 47. My fingers on my left hand were stiff and were difficult to move. People noticed that my walk was not normal. I was often asked did I hurt. I noticed nothing different about my walk. It was difficult getting up from` a chair and getting out of a car. I was diagnosed a year later ,it was the onset of tremors starting in my right hand that caused my other symptoms to be recognized as Parkinson's.. I am now 59. With the new herbal medicine i purchase from totalcureherbsfoundation .c om  was my only way to get rid of my PD,the herbal formula effectively reverse my condition and alleviate all symptoms. 

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    ReplyDelete
  14. I am a 51 year old female that just found out I have Parkinson's about a year and half, but I have been having signs of it for years, tremors, depression, body weakness. ECT. I honestly don't think my doctor was reading the signs because of my gender and age. A few years ago I had my shoulder lock up on me and I was sent to a P.T since x-rays didn't show any physical damage. My shaking was getting worse and I began falling. Only when my speech became so bad that it brought concern to my dentist was Parkinson's even considered. He phoned my doctor with his concerns about my shaking and balance problems. By this time I was forgoing shots in the back of my neck for back and neck pain to which once again I was sent to a P.T (although x-rays showed no damage) I was told I had a few spurs which were most likely causing the pain. Here I was feeling like my whole body was falling apart and doctor could not find anything wrong, maybe in was all in my head? My doctor even seemed annoyed with me and things just kept progressing and I just kept it to myself, why bother going through testing and them finding nothing? Well, it was after my second P.T called my doctor about the weakness in my legs and arms, by this time I have developed a gait in my walk and I fell more frequently. Only then did my doctor send me to a specialist and it was found that I had Parkinson's, and that I have had it for awhile. I think because I was a woman that my signs and symptoms weren't taken seriously and therefor left untreated for so long,I was taking pramipexole dihydrochloride three times daily, I Was on carbidopa levodopa but only lasted 90 minutes then wore off.I found that none of the current medications worked effective for me.I got tired of using those medication so I decided to apply natural herbs formula that was prescribed to me by my second P.T, i purchase the herbal formula from totalcureherbsfoundation. com, There has been huge progression ever since I start the treatment plan which will last for 15 weeks usage.all the symptoms and sign has begin to disappear .

    ReplyDelete
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  16. Sincerely i was so sad when my husband was diagnosed of Parkinsons disease 2 years ago, when he was 49. He had a stooped posture, tremors, right arm does not move and also a pulsating feeling in his body. He was placed on Senemet for 8 months and then Siferol was introduced and replaced the Senemet, during this time span he was also diagnosed with dementia. He started having hallucinations, lost touch with reality. Suspecting it was the medication I took him off the Siferol (with the doctor’s knowledge) and started him on PD natural herbal formula we ordered from Dr James, his symptoms totally declined over a 3 weeks use of the Dr James HERBAL Formula or Parkinsons disease natural herbal formula. He is now almost 51 and doing very well, the disease is totally reversed! my Husband was cured and now my Husband is free from Parkinsons, i went to the hospital that said there was no cure to Parkinsons and informed them about my Husband healing and they were surprised. here is the contact email ( jamesherbalformula@gmail.com ) also reach him on hangout or through his whatsapp number via +2348102574680 Regards.

    ReplyDelete
  17. I am here to express my profound warm gratitude to the herbal medicine, which I got from Dr. Imoloa. I am now living a healthy life since the past 6 months. I am now a genital herpes virus free after the herbal medication I got from him. You can contact him for your medication Via his email- drimolaherbalmademedicine@gmail.com/ whatsapp +2347081986098/ website www.drimolaherbalmademedicine.wordpress.com

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  18. Here is  my testimony on how I was cured of HIV by Dr Akhigbe,with his natural herbal medicine.  on a regular basis in efforts to help others when I could. As you may know, each donation is tested.  Well, on July 6th I had a meeting with a Red Cross representative and was told that I had HIV. “What went through your mind when you heard that "Rose" Good question reader! To be honest, I thought my life was over, that I would ever find love, get married, have children or anything normal. Lucky for me I have an amazing support system.  My family supported me then I never thought that I was invincible to STD s or pregnancy or anything else parents warn their kids about. I just didn’t think about it. I was in a monogamous relationship and thought that I asked the right questions.  We even talked about marriage Scary.  During that time I was in college and donated blood on a re as well. who helped me in search of cure through the media.there we saw a good testimony of sister 'Kate' about the good work of Dr Akhigbe natural herbal medicine cure.then I copied his email address and contacted him. A good herbalist doctor with a good heart, he is kind, loving and caring. He replied back to my message and told me what to do. After a week the doctor sent me my herbal medicine and instructed me how to take it.Yes it worked very well, after drinking it I went to the hospital for another test and everything turned negative. What a wonderful testimony I can never forget in my life. Dr Akhigbe is a man who gave me a life to live happily forever so all I want you all to believe and know that cure of HIV is real and herbs is a powerful medicine and it works and heals.  Dr Akhigbe also used his herbal medicine to cure diseases like:   HERPES, DIABETES, SCABIES, HEPATITIS A/B, STROKE, CANCER, ALS, TUBERCULOSIS, ASTHMA, PENIS ENLARGEMENT, MALARIA, LUPUS, LIVER CIRRHOSIS, DEPRESSION, HIV/AIDS, EPILEPSY, BACTERIAL, DIARRHEA, HEART DISEASES, HIGH BLOOD PRESSURE, PARKINSON'S, ALZHEIMER, COLD URTICARIA, HUMAN PAPILLOMAVIRUS,INSOMNIA,  BACTERIAL VAGINOSIS, SCHIZOPHRENIA, JOINT PAIN, STOMACH PAIN, CHROME DISEASES, CHLAMYDIA, INSOMNIA HEARTBURN, ,  THYROID, MAR BURG DISEASES, MENINGITIS, ARTHRITIS, BODY WEAK, SMALLPOX, DENGUE, FEVER, CURBS, CHANCRE, AND OTHERS VARIOUS DISEASES/ VIRUS.   You are there and you find yourself in any of these situations, kindly contact Dr Akhigbe now to help you get rid of it. Here is his email address:
       drrealakhigbe@gmail.com      or you can write to him on whats app with his phone number:   +2349010754824.
      My appreciation is to share his testimony for the world to know the good work Dr Akhigbe has done for me and he will do the same for you.
       

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  19. There is a safe & effective Natural Herbal Medicine. For Total Cure Call    +2349010754824,  or email him   drrealakhigbe@gmail.com       For an Appointment with (Dr.) AKHIGBE contact him. Treatment with Natural Herbal Cure. For:Dengue Fever, Malaria. Painful or Irregular Menstruation. HIV/Aids. Diabetics. Vaginal Infections. Vaginal Discharge. Itching Of the Private Part. Breast Infection. Discharge from Breast. Breast Pain & Itching. Lower Abdominal Pain. No Periods or Periods Suddenly Stop. Women Sexual Problems. High Blood Pressure Chronic Disease. Pain during Sex inside the Pelvis. Pain during Urination. Pelvic Inflammatory Disease, (PID). Dripping Of Sperm from the Vagina As Well As for Low sperm count. Parkinson disease. Obesity, Lupus. Soreness/Injury  Cancer.  Tuberculosis.  Zero sperm count. Bacteria, Impotence Fertility,Protoplasmic, Diarrhea. Hepatitis A&B, Rabies. Asthma.  Quick Ejaculation. Gallstone, Cystic Fibrosis, Schizophrenia, Crubs, Cirrhosis,  Premature Ejaculation. Herpes. Joint Pain. Stroke. Cornelia Disease, Weak Erection. Ovarian problem,  HeartBurn, Erysipelas, Thyroid, Relapsing polychondritis,  Discharge from Penis. Bronchial Problem,  HPV.  Hepatitis A and B. STD. Smallpox, Staphylococcus + Gonorrhea + Syphilis. Heart Disease.  Pile-Hemorrhoid.rheumatism,  Impotence, thyroid, Autism, Depression,  Sepsis Bacteria,  Penis enlargement, Prostate Problem,  Waist & Back Pain.  Male Infertility and Female Infertility. Etc. Take Action Now. contact him & Order for your Natural Herbal Medicine:  +2349010754824  and email him    drrealakhigbe@gmail.com    Note For an Appointment with (Dr.) AKHIGBE.I suffered in Cancer for a year and three months dying in pain and full of heartbreak. One day I was searching through the internet and I came across a testimony of herpes cure by doctor Akhigbe. So I contacted him to try my luck, we talked and he sent me the medicine through courier service and with instructions on how to be drinking it.To my greatest surprise drinking the herbal medicine within three weeks I got the changes and I was cured totally. I don't really know how it happens but there is power in Dr Akhigbe herbal medicine. He is a good herbalist doctor.

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  20. There is a safe & effective Natural Herbal Medicine. For Total Cure Call    +2349010754824,  or email him   drrealakhigbe@gmail.com       For an Appointment with (Dr.) AKHIGBE contact him. Treatment with Natural Herbal Cure. For:Dengue Fever, Malaria. Painful or Irregular Menstruation. HIV/Aids. Diabetics. Vaginal Infections. Vaginal Discharge. Itching Of the Private Part. Breast Infection. Discharge from Breast. Breast Pain & Itching. Lower Abdominal Pain. No Periods or Periods Suddenly Stop. Women Sexual Problems. High Blood Pressure Chronic Disease. Pain during Sex inside the Pelvis. Pain during Urination. Pelvic Inflammatory Disease, (PID). Dripping Of Sperm from the Vagina As Well As for Low sperm count. Parkinson disease. Obesity, Lupus. Soreness/Injury  Cancer.  Tuberculosis.  Zero sperm count. Bacteria, Impotence Fertility,Protoplasmic, Diarrhea. Hepatitis A&B, Rabies. Asthma.  Quick Ejaculation. Gallstone, Cystic Fibrosis, Schizophrenia, Crubs, Cirrhosis,  Premature Ejaculation. Herpes. Joint Pain. Stroke. Cornelia Disease, Weak Erection. Ovarian problem,  HeartBurn, Erysipelas, Thyroid, Relapsing polychondritis,  Discharge from Penis. Bronchial Problem,  HPV.  Hepatitis A and B. STD. Smallpox, Staphylococcus + Gonorrhea + Syphilis. Heart Disease.  Pile-Hemorrhoid.rheumatism,  Impotence, thyroid, Autism, Depression,  Sepsis Bacteria,  Penis enlargement, Prostate Problem,  Waist & Back Pain.  Male Infertility and Female Infertility. Etc. Take Action Now. contact him & Order for your Natural Herbal Medicine:  +2349010754824  and email him    drrealakhigbe@gmail.com    Note For an Appointment with (Dr.) AKHIGBE.I suffered in Cancer for a year and three months dying in pain and full of heartbreak. One day I was searching through the internet and I came across a testimony of herpes cure by doctor Akhigbe. So I contacted him to try my luck, we talked and he sent me the medicine through courier service and with instructions on how to be drinking it.To my greatest surprise drinking the herbal medicine within three weeks I got the changes and I was cured totally. I don't really know how it happens but there is power in Dr Akhigbe herbal medicine. He is a good herbalist doctor.

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  21. I’m here to testify about what Dr. Omola did for me. I have been suffering from (GENITAL HERPES VIRUS) disease for the past 3 years and had constant pain and inching, especially in my private part. During the first year, I had faith in God that i would be cured someday.This disease started circulating all over my body and I have been taking treatment from my doctor, few weeks ago I came across a testimony of Mary on the internet testifying about a Man called Dr. Omola on how he cured her from 5 years HSV 2. And she also gave the email address of this man, advise anybody to contact him for help on any kind of diseases that he would be of help, so I emailed him telling him about my (HSV 2) he told me not to worry that I was going to be cured!! Well, I never doubted him I have faith he can cure me too,, Dr. Omola prepared and sent me Healing Oil, Soap, roots and herbs which I took. In the first one week, I started experiencing changes all over me, after four weeks of using his Roots/ Herbs, Oil and Soap, I was totally cured. no more inching , pain on me anymore as Dr. Omola assured me. After some time I went to my doctor to do another test behold the result came out negative. So friends my advise is if you have such disease or know anyone who suffers from it or any other disease like HPV, HBV, ALS, HBP, CANCER etc. you can contact Dr. Omola for help via dr.omolaherbalhome@gmail.com or whatsapp +2348118116254.

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